The successful combination of high-end phage display technology with precise gene libraries allows the efficient generation and rapid screening of peptide libraries with extraordinary complexity. These phage libraries allow for example precise epitope mapping and further characterisation of antibody binding properties by epitope fingerprinting to a hence unmatched precision. EPITOPIC’s technology allows the precise identification of binding sites and the modifications accepted for antibody binding. This should become an essential tool for antibody validation, both for research reagents in clinical applications as well as for therapeutic antibodies with respect to QC and patentability. The exact knowledge of antibody epitopes is also important for understanding autoimmune diseases (e.g. multiple sclerosis or rheumatic disease) or infectious diseases and for the development of vaccines as well as for validation and application of antibodies as research tools.
EPITOPIC supports customers with these technologies and services to speed up research and enables substantially new ways in product development. The insights gained with our technologies are adding significant value to many different products.
- Reliable epitope identification
- Characterize even minor binding details
- Position your antibody product against the competitor’s
FLAG® and anti-FLAG® are registered trademarks of Sigma-Aldrich Co. LLC.